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Calcitonin (human)

CAS No. 21215-62-3

Calcitonin (human)( —— )

Catalog No. M30719 CAS No. 21215-62-3

Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Calcitonin (human)
  • Note
    Research use only, not for human use.
  • Brief Description
    Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.
  • Description
    Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Female Sprague-Dawley ratsDosage:2 mg/kg Administration:Oral gavage; 2 mg/kg; once daily; 9 weeks Result:Suppressed ovariectomy-induced cartilage degradation (P<0.001) compared with the carrier control.Prevented cartilage erosion compared with treatment with the carrier alone (P<0.01), and the extent of erosions was comparable with that in sham-operated animals.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    CGRP Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21215-62-3
  • Formula Weight
    3417.87
  • Molecular Formula
    C151H226N40O45S3
  • Purity
    >98% (HPLC)
  • Solubility
    water:2 mg/mL
  • SMILES
    [H]N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC1=O)[C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Foster (1968) Calcitonin. A review of experimental and clinical investigations. Postgrad.Med.J. 44 411 PMID:
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